Dihydromyricetin (DHM) Powder For Wholesale

Dihydromyricetin（DHM） is a natural compound, mainly extracted from the fruit of Hovenia dulcis and the dried stems and leaves of Ampelopsis grossedentata. It belongs to the flavonoid class. It is usually found in the form of white crystalline powder or solid, with good chemical stability and certain solubility. Through advanced extraction and purification technology, its purity and quality are ensured to meet strict international standards. The chemical structure of this compound is clear, with the molecular formula of C15H12O8 and a molecular weight of approximately 316.25. Its physicochemical properties make it potentially valuable in a variety of industrial applications. The main active ingredient is flavonoids, which has various unique effects such as scavenging free radicals, anti-oxidation, anti-thrombus, anti-tumor, anti-inflammatory, etc. 

Besides the general properties of flavonoids, dihydromyricetin can also relieve alcohol poisoning, prevent alcoholic liver and fatty liver, inhibit liver cell deterioration, and reduce the incidence of liver cancer. It is a good product to protect the liver and cure the hangover.

Properties and Specifications

Chemical Formula: C₁₅H₁₂O₈

Molecular Weight: 320.25

Appearance: High-purity dihydromyricetin is typically a white to off-white powder, appearing as needle-like crystals (in ethanol).

Stability: Stable under neutral and acidic conditions, with good thermal stability. However, it undergoes irreversible oxidation at temperatures above 100°C.

Detection Method: Purity is typically determined using HPLC (High-Performance Liquid Chromatography).

Solubility: Easily soluble in hot water, hot ethanol, and acetone. Sparingly soluble in ethyl acetate, and insoluble in chloroform and petroleum ether.

Purity Specifications: Common purity specifications include 30%, 50%, and 98%.

Solubility Specifications: Water-soluble specifications are available (e.g., 30% water-soluble).

Packaging Specifications: Typically packaged in 20mg (standard), 1kg/bag, 25kg/cardboard drum, and other specifications.

COA

Dihydromyricetin: Biological Activities and Efficacy

Antioxidant and Anti-inflammatory Effects: DHM exhibits free radical scavenging, antioxidant, and anti-inflammatory properties, which contribute to delaying aging.

Liver Protection and Alcohol Detoxification: By increasing the activity of aldehyde dehydrogenase, dihydromyricetin accelerates alcohol metabolism, reduces alcohol-induced liver damage, and improves hepatocyte injury, thus preventing alcoholic liver disease.

Anti-tumor Effects: In vitro experiments have shown that dihydromyricetin can inhibit the proliferation of tumor cells and induce apoptosis. It has also demonstrated anti-tumor effects in tumor models of leukemia and nasopharyngeal carcinoma.

Regulation of Blood Lipids and Glucose: Dihydromyricetin can reduce blood lipid levels and inhibit blood glucose elevation, which is of great significance for the auxiliary treatment of diabetes.

Antibacterial Effects: Dihydromyricetin has inhibitory effects on a variety of bacteria and fungi, including Bacillus subtilis, Staphylococcus aureus, and Escherichia coli.

Immune Enhancement: Dihydromyricetin can activate immune cells and promote the production of immune factors.

Neuroprotection: Dihydromyricetin can protect nerve cells from toxic damage by regulating receptors such as GABA and NMDA, thereby protecting cognitive function.

Anti-inflammatory Effects: Dihydromyricetin has anti-inflammatory properties and can inhibit the activation of pro-inflammatory cytokines and NF-κB.

Applications

Health Food and Dietary Supplements: As a natural antioxidant and alcohol-relieving ingredient, dihydromyricetin is widely used in various product forms, including tablets, capsules, and oral powders.

Pharmaceutical Field: Dihydromyricetin is being explored for the development of novel drugs targeting cardiovascular diseases, cancer, and other conditions.

Animal Feed: As an additive in animal feed, dihydromyricetin has shown potential in improving meat quality and shortening animal growth cycles.

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