Description

Fisetin is primarily derived from plants in the Anacardiaceae family, such as Rhus succedanea (Japanese wax tree) or Cotinus coggygria Scop. (smoke tree). In terms of extraction processes, solvent extraction is commonly used, leveraging its solubility in specific organic solvents to separate fisetin from the plant material. This is followed by a series of purification steps, such as column chromatography and recrystallization, to obtain high-purity fisetin products that meet the quality requirements for food color additives. Due to its natural origin, it aligns with the current consumer trend towards natural and safe food additives.

Fisetin is a naturally occurring flavonoid compound. It appears as yellow needle-like crystals and, in terms of chemical properties, is poorly soluble in water and some common organic solvents such as petroleum ether, but readily soluble in organic solvents such as acetone and ethyl acetate. This unique solubility profile has a significant impact on the extraction, purification, and dispersion of fisetin in food matrices during its application as a food color additive.

JIUYUAN BIOTECH supplies 50% and 98% Fisetin powder for sale. which have been certificated with the third-party test report. Please contact us to get sample and more details.

Comparison Advantages of Fisetin over Other Colorants

1. Safety Aspect

Compared to some synthetic colorants, such as azo dyes, fisetin, as a natural pigment, has higher safety. Synthetic colorants may have potential health risks after long-term consumption in large quantities, such as some azo dyes may produce harmful substances in the body after metabolism. Fisetin, on the other hand, is derived from natural plants. Under normal usage doses, a large number of toxicological studies have shown that it has minimal harm to human health and is considered a relatively safe food additive.

2. Color Stability and Color Modulation Characteristics

Fisetin has good color stability in different pH environments and light conditions. Compared with some natural pigments such as chlorophyll, chlorophyll is prone to discoloration in an acidic environment. At the same time, fisetin can maintain a relatively stable yellow color in a wider pH range (such as 3-8). At the same time, fisetin can be compounded with other natural pigments such as carotenoids to modulate color, creating more diverse color effects and meeting the personalized needs of different food products for color. This is difficult for many single pigments to achieve.

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Fisetin: A Natural Flavonoid with Diverse Health Benefits

Fisetin is a naturally occurring flavonoid compound that offers a wide range of health benefits, including:

Antioxidant Activity

Fisetin exhibits potent antioxidant capabilities, effectively scavenging free radicals and protecting cells from oxidative damage. It also enhances glutathione levels, further optimizing the body's antioxidant defenses.

Anti-inflammatory Effects

Fisetin can suppress the production and release of various inflammatory mediators, such as prostaglandins, leukotrienes, and cytokines. This action helps reduce inflammation and alleviate pain and discomfort. These properties suggest its potential therapeutic use in managing inflammatory conditions like arthritis and gastritis.

Cognitive and Memory Enhancement

Fisetin can cross the blood-brain barrier, triggering antioxidant mechanisms and shielding brain cells from oxidative stress. It also improves cognitive function and long-term memory by boosting glutathione levels, supporting the growth of new brain cells, and optimizing brain cell structure and function.

Anti-tumor Properties

Research indicates that fisetin can inhibit the proliferation and migration of tumor cells, induce apoptosis (programmed cell death) in cancer cells, and strengthen the immune system's anti-tumor response.

Cardiovascular Protection

Fisetin contributes to cardiovascular health by lowering blood lipid levels, inhibiting platelet aggregation, and preventing thrombus formation (blood clots).

Skin Health

In the realm of cosmetics, fisetin's antioxidant and anti-inflammatory properties can protect the skin from environmental damage, reduce the appearance of age spots and wrinkles, and delay skin aging.

Other Health Benefits

Fisetin also exhibits hepatoprotective (liver-protective) and immunomodulatory effects, bolstering the body's resistance to infections and diseases.

Fisetin: Applications in Food, Cosmetics, and Healthcare

Fisetin is a versatile natural compound with applications across various industries, including food, cosmetics, and healthcare. Here's a detailed overview:

1. Food Industry

Fisetin offers several valuable applications as a natural food additive:

Natural Coloring Agent: Fisetin's yellow to orange-yellow hue makes it a suitable natural pigment for enhancing the color and appearance of food products. It can be used in baked goods, confectionery, and beverages to impart an appealing color.

Antioxidant and Preservative: Fisetin's potent antioxidant and antibacterial properties contribute to extending the shelf life of food products. It is often used in meat products and fried foods to inhibit fat and protein oxidation while reducing microbial contamination.

Nutritional Fortification: Fisetin's rich content of bioactive compounds makes it a valuable nutritional fortifier. It can be added to infant food and health supplements to improve their nutritional value.

2. Cosmetic Industry

Fisetin is widely used in cosmetics due to its diverse beneficial properties:

Antioxidant and Anti-inflammatory Agent: Fisetin's strong antioxidant and anti-inflammatory effects help neutralize free radicals, reduce oxidative damage to the skin, and alleviate skin inflammation.

Skin Brightening and Anti-aging Ingredient: Fisetin can inhibit tyrosinase activity, reducing melanin production and improving uneven skin tone and age spots. It also stimulates collagen synthesis, enhancing skin elasticity and firmness.

Natural Hair Dye: Fisetin can serve as a natural hair dye, offering a less harmful alternative for changing hair color.

Skincare Product Ingredient: Fisetin is incorporated into various skincare products like creams, serums, and masks to improve skin texture, reduce wrinkles, and delay skin aging.

3. Healthcare Industry

Fisetin holds significant potential in the pharmaceutical and healthcare sectors:

Antioxidant and Anti-inflammatory Drug: Fisetin's potent antioxidant and anti-inflammatory properties can be harnessed to develop drugs for preventing and treating various diseases.

Anti-tumor and Hepatoprotective Drug: Research suggests that fisetin exhibits anti-tumor activity by inhibiting tumor cell growth and spread. It also promotes liver cell metabolism and repair, protecting liver function.

Health Supplement Ingredient: Fisetin can be used as a component in functional foods or health supplements to boost immunity and improve cardiovascular health.