Wholesale Natural Phosphatidylserine (PS) Powder

Phosphatidylserine (PS) Powder is a high-purity phospholipid nutritional supplement widely used in health products, functional foods, and pharmaceuticals. As a key component of cell membranes, PS plays a vital role, particularly in nerve cells, by helping to maintain membrane integrity and fluidity. This supports cognitive functions, memory, and emotional balance.

Our PS Powder is produced using advanced enzymatic or microbial fermentation processes, ensuring high purity and bioactivity. The raw materials are derived from natural plant sources (such as soybeans or sunflowers) or egg yolks, and are guaranteed to be additive-free and contaminant-free, meeting international food safety standards.

PS Powder exhibits excellent solubility and stability, readily blending with other formula ingredients for various dosage forms, including softgels, tablets, and powders. As a market-recognized ingredient, our PS Powder provides purchasers with reliable quality assurance and flexible application options, making it an ideal choice for developing high-quality health products and functional foods. Phosphatidylserine 20%, 50% and 70% are light yellow powders, soluble in most non-polar solvents and insoluble in anhydrous.

Key Features and Benefits:

High Purity: Produced using advanced enzymatic or microbial fermentation processes.

Natural Origin: Derived from plant sources (soybean or sunflower) or egg yolks.

Cognitive Support: Helps maintain cell membrane integrity and fluidity, supporting cognitive functions, memory, and emotional balance.

Versatile Applications: Suitable for various dosage forms, including softgels, tablets, and powders.

Quality Assurance: Meets international food safety standards.

Ideal for:

Health supplements

Functional foods

Nootropics

Cognitive enhancement products

Support customized specifications, contact us get sample or more details.

The product has been tested after production.  We guarantee that all supplied products have been tested, support third-party testing, support free sample testing, maximize customer rights, and lay a solid foundation for us to achieve long-term friendly cooperation, and we will provide you with the best price.

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Phosphatidylserine (PS) vs. Phosphatidylcholine (PC)

Both phosphatidylserine (PS) and phosphatidylcholine (PC) are important members of the phospholipid family, but they exhibit some differences in structure, function, and applications. The following is a detailed comparison:

1. Chemical Structure

PS: Its head group contains a serine residue, which carries a negative charge and is more hydrophilic.

PC: Its head group contains a choline residue, which is neutral and less hydrophilic.

2. Physiological Functions

PS:

Mainly located on the inner layer of the cell membrane, it plays an important regulatory role in the fluidity and permeability of the cell membrane.

In the nervous system, PS plays an important role in memory, emotional stability, and neuroprotection, and is often used to improve cognitive function and relieve stress.

PC:

It is one of the main components of the cell membrane and is widely present on the outer layer of the cell membrane.

Plays an important role in liver metabolism and helps with fat transport and cholesterol metabolism.

3. Applications

PS:

It is often used in health products and functional foods to improve cognitive function, relieve stress, and delay aging.

In the pharmaceutical field, PS can be used for neuroprotection and treatment of neurodegenerative diseases.

PC:

Widely used in the food industry as an emulsifier and stabilizer.

Used in health products for liver protection and cardiovascular health support.

4. Sources

PS: Mainly extracted from soybeans, sunflowers, or egg yolks.

PC: Mainly derived from soybean lecithin, egg yolk lecithin, or synthesized.

5. Safety and Regulations

PS: It has been certified as a safe nutritional supplement by the drug regulatory agencies of many countries, such as the GRAS certification of the US FDA.

PC: As a food additive and health product ingredient, it is widely used in the global market.

Summary

In summary, although both PS and PC belong to phospholipids, there are obvious differences in their chemical structure, physiological functions, and application fields. PS is more related to the nervous system and cognitive functions, while PC is more widely used in liver metabolism and the food industry.

Production Processes of Phosphatidylserine (PS)

The production of phosphatidylserine (PS) primarily involves the following processes:

1. Microbial Fermentation

Microbial fermentation is currently one of the important methods for producing phosphatidylserine. By constructing recombinant strains (such as Escherichia coli or Streptomyces) that can efficiently express phosphatidylserine synthase (PSS), cells can synthesize and accumulate phosphatidylserine under optimized fermentation conditions. For example, research at Jiangnan University, through strain screening, obtained a Streptomyces cinnamoneus strain that highly produces phospholipase D. This enzyme was used to prepare phosphatidylserine from lecithin through a phosphate group transfer reaction.

2. Enzymatic Catalysis

Enzymatic catalysis uses phospholipase D to convert phosphatidylcholine (PC) into phosphatidylserine. This method typically involves immobilizing phospholipase D or directly adding it to the reaction system, and optimizing reaction conditions (such as pH, temperature, substrate concentration, etc.) to improve conversion efficiency. For example, studies have shown that recombinant Pichia pastoris whole-cell biocatalysts overexpressing phospholipase D can achieve efficient synthesis of phosphatidylserine in an aqueous system.

3. Extraction and Purification

Regardless of the production method used, extraction and purification are key steps in the production of phosphatidylserine. In modern processes, technologies such as supercritical fluid extraction, membrane separation, and high-performance liquid chromatography are widely used to improve the purity and yield of PS.

Key Considerations in JIUYUAN BIOTECH PS Production:

Strain Selection: For microbial fermentation, selecting strains with high PSS expression and efficient PS production is crucial.

Enzyme Activity: For enzymatic catalysis, the activity and stability of phospholipase D are essential for efficient conversion.

Process Optimization: Optimizing fermentation or reaction conditions, as well as extraction and purification processes, is critical to maximizing PS yield and purity.

Cost-Effectiveness: The overall cost of production, including raw materials, energy consumption, and equipment, needs to be considered for industrial-scale production.

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